Figure 3
Effect of PGE2 in inducing IL-23 production in DCs. Transwell co-cultures were set up as above in the absence (none; vehicle control) or the presence of (a) COXs inhibitors (SC560, 100 nM, or indomethacin, 100 nM) or (b) PGE2 receptor antagonists (AH6809, 10 uM, and AH23848, 10 uM). Data given as the means ± SE from three-five independent experiments performed with DCs from different donors. Mann-Whitney U test was used and for pair-wise comparisons only. *p < 0.05, **p < 0.01.
