Figure 2
From: Altered aspects of anxiety-related behavior in kisspeptin receptor-deleted male mice
Open field trial performance of gonadectomized (GDX) and intact KISS1R-KO mice. Different letters above histograms indicate statistically significant differences between GDX control (GDX C; N = 9), GDX KISS1R-KO (GDX KO; N = 7), intact control (Intact C, N = 8) and intact KISS1R-KO rescue (Intact KO, N = 9) mice. Bars with *** above GDX group indicate significant difference between all GDX and all intact mice for each parameter (P < 0.001, 2-way ANOVA). (A) Histograms showing average total distance travelled over the 3 trials. b vs. a = P < 0.05, Tukey’s post-hoc multiple comparisons. (B) Histograms showing the average number of crossings into the inner quadrant (center) over the 3 trials. b vs. a = P < 0.001, Tukey’s post-hoc multiple comparisons. (C) Histograms showing the average percentage of time spent in the inner quadrant over the 3 trials. b vs. a = P < 0.01, Tukey’s post-hoc multiple comparisons.
