Figure 2 | Scientific Reports

Figure 2

From: Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development

Figure 2

Brca1 I26A mutation is not sufficient for rescuing the developmental defects of Cobra1-KO mammary glands. (a) Whole mounts of mammary glands from 8-week virgin mice. Red dash line highlights the boundary of the ductal area. Images are representatives of at least 4 animals in each group. Scale bars = 1 mm. (b) Measurement of average ductal length of 8-week mammary glands. The numbers of animals used are: WT = 4, CKO = 6, CKO-E11− = 7, CKO-I26A = 4. Error bars represent s.e.m. Student’s t-test was used to calculate P value. **P < 0.01, ns: not significant.

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