Figure 3

Generation of CKO-S1598F compound mutant mice. (a) Chi-square analysis for female progenies obtained from the breeding strategies indicated. The two-tailed P values are calculated by Chi-square goodness-of-fit test with 5 degrees of freedom. (b) Whole mounts of mammary glands from 8-week virgin mice. Red dash line highlights the boundary of the ductal area. Scale bars = 1 mm. Mammary ductal growth of a sole surviving CKO-S1598F female mouse is shown.