Table 2 Comparison of consistency of qFibrosis with Ishak staging in paired liver biopsies from chronic hepatitis B patients after antiviral therapy.
Ishak fibrosis score Pre → Post-treatment | qFibrosis n = 162 patients | Total n = 162 | Consistency (%) | Total Consistency (%) | Consistency in advanced fibrosis and cirrhosis (%) | |||
|---|---|---|---|---|---|---|---|---|
Regression | Stable | Progression | ||||||
Regression | n = 12 | 91.7 | 100 | |||||
↓ ≥ 2 stage | 2/3 → 0/1 | 3 | 1 | 0 | 4 | 75.0 | ||
4 → 2 | 4 | 0 | 0 | 4 | 100 | |||
5/6 → 3/4 | 4 | 0 | 0 | 4 | 100 | |||
Regression | n = 57 | 66.7 | 82.8 | |||||
↓ = 1 stage | 1/2 → 0/1 | 4 | 7 | 0 | 11 | 36.4 | ||
3 → 2 | 10 | 6 | 1 | 17 | 58.8 | |||
4 → 3 | 17 | 4 | 1 | 22 | 77.3 | |||
5/6 → 4/5 | 7 | 0 | 0 | 7 | 100 | |||
Stable | n = 84 | 34.5 | 13.8 | |||||
No change | 2 → 2 | 8 | 10 | 5 | 23 | 43.5 | ||
3 → 3 | 11 | 15 | 6 | 32 | 46.9 | |||
4 → 4 | 9 | 3 | 3 | 15 | 20.0 | |||
5/6 → 5/6 | 12 | 1 | 1 | 14 | 7.1 | |||
Progression | n = 9 | 66.7 | 75.0 | |||||
↑ ≥ 1 stage | 1/2 → 2/3 | 0 | 2 | 3 | 5 | 60.0 | ||
3 → 4/5 | 0 | 0 | 2 | 2 | 100 | |||
4 → 5 | 0 | 1 | 1 | 2 | 50.0 | |||
