Table 1 Correspondence between kinetic and phenotypic families.

From: Prime and Boost Vaccination Elicit a Distinct Innate Myeloid Cell Immune Response

Kinetic family

Composition

Kinetic pattern

Phenotypic family

Cell population

I

Granulocytes 14; 11, 19, and 1 Monocytes-DCs 30

Neutrophils, including poorly to moderately activated neutrophils and uncharacterized APCs

Post-prime enrichment

III

Granulocytes 8; 4 and 13; 3

II

Granulocytes 6 and 2; 7 and 5 Monocytes-DCs 35 and 41

Neutrophils, including moderately to highly activated neutrophils, highly activated monocytes, CCR5highCXCR4highcDCs, and inflammatory cDCs/non-classical monocytes

Post-boost enrichment

IV

Granulocytes 9 and 15

VI

Granulocytes 12 and 16

X

Monocytes-DCs 24 and 32; 39 and 29

V

Granulocytes 20; 17 and 10 Monocytes-DC 42 and 25

Neutrophils, poorly to highly activated monocytes, HLA-DRlowcDCs, and uncharacterized APCs

Post-prime and post-boost enrichment

VIII

Granulocytes 21 Monocytes-DCs 38, 36 and 22

IX

Monocytes-DCs 23 and 34; 31; 27

VII

Granulocytes 18

Basophils, pDCs, CD14lowmonocytes, and cDCs including HLA-DRlowand CD64highcDCs

No/heterogeneous enrichment

XI

Monocytes-DCs 28; 37 and 26

XII

Monocytes-DCs 33 and 40

  1. For each kinetic family, its composition in terms of phenotypic families (listed from top to bottom from the corresponding heatmaps (Fig. 4) and separated by “;” to designate their being from different superfamilies) and its main cell populations and phenotypes, as well as its kinetic pattern, as classified in Fig. 5a, are indicated.