Figure 3 | Scientific Reports

Figure 3

From: PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry

Figure 3

LtoE-shifted regions upon PREP1 down-regulation.Repliseq profiles (S1, early-, to S6, late-S phase) of siLuc cells (pale blue tracks) and siPREP1 (superimposed red tracks), showing a representative late-to-early (LtoE)-shifted region identified by visual inspection (empty blue box). Red and blue arrows indicate higher levels of BrdU incorporation within siPREP1 (in S2 window) or siLuc cells (in S5), respectively. Red boxes indicate late-to-early (LtoE)-shifted regions identified by bioinformatic analysis.

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