Figure 4 | Scientific Reports

Figure 4

From: PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry

Figure 4

Mapping of temporally-shifted regions in siPREP1 cells. Representative genomic region (17 Mb in length) from the UCSC Genome Browser showing (top to bottom): the S50 profile and S50 valleys of siLuc cells (light blue track and boxes, respectively); Temporal Transition Regions (TTR, black) and Late-Replicating Regions (LRR, green horizontal lines); LtoE-shifted regions identified in siPREP1 cells (red boxes); Lamin B1-bound DNA (deep blue signals corresponding to positive log2-ratio scores14); EtoL-shifted regions identified in siPREP1 cells (dark blue boxes); position of RefSeq genes, as indicated.

Back to article page