Table 3 LtoE contigs are enriched in Lamin-Associated-Domains and depleted in PREP1 binding sites.

From: PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry

 

Number

%

p-value*

LtoE contigs with LaminB1 binding sites

1,237/1,717

72

<2.2e-16 (enrichment of LaminB1-positive LtoE contigs)

PREP1 peaks within LtoE conting in siLuc cells

471/3,909

12

<2.2e-16 (depletion of PREP1 peaks within LtoE contigs)

  1. *Fisher Test vs. random genomic contigs with 100 iterations (see Methods).
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