Table 2 Isothermal Calorimetric Data of interaction of Peptide 2 with hDHFR.
From: Optimized peptide based inhibitors targeting the dihydrofolate reductase pathway in cancer
Physical parameters obtained from ITC data | |
|---|---|
Ka(M−1) | 1.1 ± 0.1 × 106 |
ΔH (kJ/mol) | −70 ± 1 |
TΔS (kJ/mol) | −36.25 ± 0.01 |
ΔG (kJ/mol) | −34 ± 1 |
