Figure 3
From: Ixr1 Regulates Ribosomal Gene Transcription and Yeast Response to Cisplatin
IXR1 deletion affects transcription of other yeast general regulators. (A) Regulatory network showing the role that Ixr1 has, represented in circular or extended layouts of the major transcriptional regulators Tec1 (red), Sok2 (orange), Abf1 (green) and Sfp1 (dark blue). Dark dashed lines indicate direct nodes between general regulators and rhombus correspond to genes that encode transcriptional regulators. Genes related to translation [GO:0006412] are light green, ncRNA metabolism [GO:0034660] pink, transcription [GO:0006351] light blue, transport [GO:0006810] violet, hexose metabolism [GO:0019318] brown, sexual reproduction [GO:0019953] yellow, and others grey. (B) qPCR confirmation of the regulation exerted by Ixr1 on major nodes; analysis of HHO1 expression was included as a non-regulated control. Wt, W303 strain; W/O, without cisplatin treatment.
