Table 3 Imaging and Clinico-Pathological Factors between Patients with and without Advanced ALN metastases after Neoadjuvant Chemotherapy.
Characteristics | Patients without Advanced ALN metastases (nā=ā96) | Patients with Advanced ALN metastases (nā=ā12) | P Value |
---|---|---|---|
Age, years* | 46.2ā±ā8.5 | 48.3ā±ā7.9 | 0.421 |
Initial clinical T stages | Ā | Ā | 0.230 |
Ā Ā T1 | 13 (13.5%) | 0 | Ā |
Ā Ā T2 | 60 (62.5%) | 8 (66.7%) | Ā |
Ā Ā T3 | 18 (18.8%) | 3 (25.0%) | Ā |
Ā Ā T4 | 5 (5.2%) | 1 (8.3%) | Ā |
Initial clinical N stages | Ā | Ā | 0.195 |
Ā Ā N0 | 6 (6.2%) | 0 | Ā |
Ā Ā N1 | 38 (39.6%) | 4 (33.3%) | Ā |
Ā Ā N2 | 40 (41.7%) | 5 (41.7%) | Ā |
Ā Ā N3 | 12 (12.5%) | 3 (25.0%) | Ā |
Histologic grade | Ā | Ā | 0.937 |
Ā Ā Low to moderate | 73 (76.0%) | 9 (75.0%) | Ā |
Ā Ā High | 23 (24.0%) | 3 (25.0%) | Ā |
HR status | Ā | Ā | 0.890 |
Ā Ā Negative | 38 (39.6%) | 5 (41.7%) | Ā |
Ā Ā Positive | 58 (60.4%) | 7 (58.3%) | Ā |
HER2 status | Ā | Ā | 0.677 |
Ā Ā Negative | 58 (60.4%) | 8 (66.7%) | Ā |
Ā Ā Positive | 38 (39.6%) | 4 (33.3%) | Ā |
Number of positive ALNs on initial staging MR imaging** | Ā | Ā | 0.015 |
Ā Ā <4 | 52 (54.2%) | 2 (16.7%) | Ā |
Ā Ā ā„4 | 44 (45.8%) | 10 (83.3%) | Ā |
Number of positive ALNs on restaging MR imaging** | Ā | Ā | <0.001 |
Ā Ā <2 | 86 (89.6%) | 5 (41.7%) | Ā |
Ā Ā ā„2 | 10 (10.4%) | 7 (58.3%) | Ā |
Short diameter of the largest ALN on initial staging MR imaging | Ā | Ā | 0.295 |
Ā Ā ā¤ā7.7āmm | 26 (27.1%) | 5 (41.7%) | Ā |
Ā Ā >7.7āmm | 70 (72.9%) | 7 (58.3%) | Ā |
Short diameter of the largest ALN on restaging MR imaging | Ā | Ā | 0.007 |
Ā Ā ā¤7.7āmm | 80 (83.3%) | 6 (50.0%) | Ā |
Ā Ā >7.7āmm | 16 (16.7%) | 6 (50.0%) | Ā |
Nodal SUVmax on initial staging PET/CT | Ā | Ā | 0.060 |
Ā Ā ā¤2.6 | 34 (35.4%) | 1 (8.3%) | Ā |
Ā Ā >2.6 | 62 (64.6%) | 11 (91.7%) | Ā |
Nodal SUVmax on restaging PET/CT | Ā | Ā | <0.001 |
Ā Ā ā¤1.1 | 84 (87.5%) | 5 (41.7%) | Ā |
Ā Ā >1.1 | 12 (12.5%) | 7 (58.3%) | Ā |