Table 4 Univariate and Multivariate Analyses Associated with Advanced ALN metastases after Neoadjuvant Chemotherapy.

From: Prediction of Advanced Axillary Lymph Node Metastases (ypN2-3) Using Breast MR imaging and PET/CT after Neoadjuvant Chemotherapy in Invasive Ductal Carcinoma Patients

Characteristics

Univariate OR (95% CI)

Multivariate OR (95% CI)

P value

Number of positive ALNs on initial staging MR imaging*

Ā Ā <4

1.00

1.00

Ā 

  ≄4

5.91 (1.23, 28.41)

6.04 (0.81, 45.17)

0.080

Number of positive ALNs on restaging MR imaging*

Ā Ā <2

1.00

1.00

Ā 

  ≄2

12.04 (3.21, 45.13)

8.06 (1.51, 43.02)

0.015

Short diameter of the largest ALN on restaging MR imaging

  ≤ 7.7 mm

1.00

1.00

Ā 

Ā Ā >7.7 mm

5.00 (1.43, 17.49)

4.44 (0.92, 21.37)

0.063

Nodal SUVmax on initial staging PET/CT

  ≤2.6

1.00

1.00

Ā 

Ā Ā >2.6

6.03 (0.75, 48.74)

3.06 (0.24, 39.17)

0.391

Nodal SUVmax on restaging PET/CT

  ≤1.1

1.00

1.00

Ā 

Ā Ā >1.1

9.80 (2.68, 35.86)

4.56 (0.87, 23.81)

0.072

  1. HR = hormone receptor; HER2 = human epidermal growth factor receptor 2; LN = lymph node; SUVmax = maximal standardized uptake value; OR = odds ratio; CI = confidence interval.
  2. *The positive axillary LN was considered when one or more findings were noted as follows: cortical thickness>3 mm, eccentric cortical thickening, loss of fatty hilum, and round or lobulated nodal shape at MR imaging.