Figure 5
From: A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
Docking of GSK and CDD compounds into the PanK crystal structure. (A) GSK1570606A, (B) GSK920684A, (C) GSK735826A, (D) CDD-934506, (E) CDD 823953 in ATP binding site with 2D interaction plots. All molecules are compared to the triazine ligand from the crystal structure shown as the green thin line.
