Figure 5 | Scientific Reports

Figure 5

From: Structural heterogeneity of the rat pulmonary vein myocardium: consequences on intracellular calcium dynamics and arrhythmogenic potential

Figure 5

Examples of calcium increase delay maps of calcium transients with distinct spatiotemporal shapes. These were recorded in Fluo-4 AM loaded PV CM with confocal microscopy. Pseudo colours indicate the delay between the start of the electrical field stimulation and the time of the maximum rate of rise of calcium in the cytoplasm. (A) A homogeneous and rapid increase of calcium in the whole CM following stimulation. (B) Following stimulation calcium rise occurs rapidly in some parts of the CM and later in others. (C) Calcium rises first near the plasma membrane at the periphery of the CM. Then it propagates centripetally to the centre of the CM. Calcium transients from n = 20 PV CM were analysed.

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