Figure 7 | Scientific Reports

Figure 7

From: Structural heterogeneity of the rat pulmonary vein myocardium: consequences on intracellular calcium dynamics and arrhythmogenic potential

Figure 7

Spontaneous calcium waves and induced currents in PV and LA CM. (A) Examples of calcium wave fluorescence (top traces) and simultaneous variations of the holding current at −70 mV (lower traces) in PV and LA CM. Downward deflections correspond to inward currents. (B) Inward current amplitude induced by spontaneous calcium waves occurring at rest at −70 mV. Each data point corresponds to a wave recorded in LA (open symbols, n = 242 waves, 9 CM) or in PV CM (filled symbols, n = 272 waves, 9 CM). Straight lines represent linear adjustments of the form Y = AX + B to the data points with the constraint current = 0 for F/F0 = 1. Slopes for PV and LA are statistically different (P < 0.001; Student’s t-test).

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