Table 1 Original diagnosis and IHC classification of 54 sinonasal tumours.

From: Genetic profiling of poorly differentiated sinonasal tumours

Initial diagnosis

IHC classification

Tumour entity

Differentiation

N° of Cases

Ck−Ne+

Ck+Ne+

Ck+Ne−

Ck−Ne−

ONB

Grade I

3

3

   
 

Grade II

10

5

2

3a

 
 

Grade III

6

1

5

  
 

Grade IV

5

2

2

1

 

SNEC

 

11

 

8

2

1

SNUC

 

19

 

1

18b,c

 

Total

 

24

11

18

24

1

  1. Legend. ONB: olfactory neuroblastoma; SNEC: sinonasal neuroendocrine carcinoma; SNUC sinonasal undifferentiated carcinoma; Ck: pan-cytokeratin marker (AE1/AE3); Ne: neuroendocrine markers (synaptophysin/cromogranin); aone case is also SMARCB1-deficient; bone case is also SMARCB1-deficient; cone case shows focal NUT staining.