Figure 2 | Scientific Reports

Figure 2

From: Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice

Figure 2

Vangl2Lp/+ mutation is associated with lower trabecular bone mass. µCT analysis of proximal tibial trabecular bone mass and architecture in 3-week-old male Vangl2+/+ and Vangl2Lp/+ littermates (n = 8 each). (A) Representative images of the proximal tibia showing less trabecular bone in the Vangl2Lp/+ tibia (arrows). Scale bar = 1 mm. B) BV/TV, (C) Tb.N, (D) Tb.Th, (E) Tb.Pf and (F) SMI were compared. *p < 0.05, **p < 0.01 by independent samples t-test.

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