Figure 7
Zic2Ku/+ mutation is associated with significantly smaller cortical bone mass in the proximal tibia of young male mice. SSA µCT analysis of cortical bone structure at each 1% site along the bone’s length in 3-week-old male Zic2+/+ and Zic2Ku/+ littermates (n = 8 each). (A) Ct.Ar, (B) Tt.Ar, (C) Ma.Ar, (D) Cs.Th, (E) PMI and (F) eccentricity were quantified. Blue lines indicate regions of significant differences between genotypes by mixed model analysis with Bonferroni post-hoc.
