Figure 8 | Scientific Reports

Figure 8

From: Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice

Figure 8

Genetic commonalities between neural tube defects and bone-associated genes are enriched for pathways with critical skeletal functions. (A) Schematic of the processes by which the extent of known genetic commonality was determined. (B) “Bone”, “osteoblast” and “osteoclast” associated gene ontology terms enriched in the NTD genes list. (C) LinkDB map of interacting genes in the Overlap list. (D) Signalling pathways enriched in the Overlap list.

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