Figure 3 | Scientific Reports

Figure 3

From: Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain

Figure 3

DPP4 immunoreactivity in various types of axon terminals. DPP4 immunolabelling on MAP2-stained dendritic surfaces was associated with synaptophysin (SYN) indicating that not the dendrites but the axon terminals express the receptor (row a). DPP4 is expressed by the majority of peptidergic (CGRP-containing) C primary afferent terminals (row b) and coexpression of DPP4 with SYN and VGLUT2 (row c) or VGAT (row d) suggests that DPP4 is present both in excitatory and inhibitory nerve endings. All the images are single optical sections. Scalebar: 5 μm.

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