Table 4 Quantitative comparisons (Mean ± STD(p-value)) between the RoiMod, SurphaMod and the SurMod in intra-fraction tracking and inter-fraction tracking for all the clinical cases.

From: Internal Motion Estimation by Internal-external Motion Modeling for Lung Cancer Radiotherapy

Intra-fraction tracking (Cases 1–7)

Structures

Quantitative Metrics

RoiMod

SurphaMod (vs RoiMod)

SurMod (vs RoiMod/SurphaMod)

Tumor

COM(mm)

1.6 ± 1.2

1.3 ± 1.0(0.041)

1.3 ± 1.0(0.043/> 0.05)

DC

0.87 ± 0.08

0.90 ± 0.07(0.064)

0.90 ± 0.07(0.038/> 0.05)

PE

0.26 ± 0.17

0.21 ± 0.15(0.060)

0.20 ± 0.15(0.038/> 0.05)

HD(mm)

5.7 ± 1.7

5.3 ± 1.6(0.082)

5.2 ± 1.5(0.049/> 0.05)

Lung

COM(mm)

2.3 ± 1.8

2.3 ± 1.6(>0.05)

2.1 ± 1.4(>0.05/> 0.05)

DC

0.96 ± 0.02

0.97 ± 0.01 (<0.001)

0.97 ± 0.01 (<0.001/> 0.05)

PE

0.07 ± 0.03

0.06 ± 0.03 (<0.001)

0.06 ± 0.02 (<0.001/> 0.05)

HD(mm)

16.1 ± 6.2

14.7 ± 5.7(0.026)

15.2 ± 5.4(0.163/> 0.05)

Inter-fraction tracking (Cases 8–11)

Structures

Quantitative Metrics

RoiMod

SurphaMod ( vs RoiMod)

SurMod (vs RoiMod/SurphaMod)

Tumor

COM(mm)

2.1 ± 2.2

1.3 ± 1.3(0.028)

1.2 ± 1.2(0.020/> 0.05)

DC

0.84 ± 0.12

0.88 ± 0.09(>0.05)

0.89 ± 0.08(0.015/> 0.05)

PE

0.37 ± 0.33

0.25 ± 0.21(>0.05)

0.23 ± 0.19(0.032/> 0.05)

HD(mm)

7.2 ± 2.6

5.7 ± 1.2(0.026)

5.6 ± 1.1(0.013/> 0.05)

Lung

COM(mm)

4.3 ± 3.0

3.0 ± 2.3(0.016)

2.3 ± 1.7 (<0.001/> 0.05)

DC

0.95 ± 0.03

±0.96 ± 0.02(0.008)

0.97 ± 0.01 (<0.001/<0.001)

PE

0.11 ± 0.05

0.08 ± 0.04(0.004)

0.06 ± 0.02 (<0.001/<0.001)

HD(mm)

20.0 ± 8.3

16.7 ± 6.9(0.069)

15.5 ± 5.9 (<0.001/> 0.05)