Table 4 Quantitative comparisons (Mean ± STD(p-value)) between the RoiMod, SurphaMod and the SurMod in intra-fraction tracking and inter-fraction tracking for all the clinical cases.
From: Internal Motion Estimation by Internal-external Motion Modeling for Lung Cancer Radiotherapy
Intra-fraction tracking (Cases 1–7) | ||||
---|---|---|---|---|
Structures | Quantitative Metrics | RoiMod | SurphaMod (vs RoiMod) | SurMod (vs RoiMod/SurphaMod) |
Tumor | COM(mm) | 1.6 ± 1.2 | 1.3 ± 1.0(0.041) | 1.3 ± 1.0(0.043/> 0.05) |
DC | 0.87 ± 0.08 | 0.90 ± 0.07(0.064) | 0.90 ± 0.07(0.038/> 0.05) | |
PE | 0.26 ± 0.17 | 0.21 ± 0.15(0.060) | 0.20 ± 0.15(0.038/> 0.05) | |
HD(mm) | 5.7 ± 1.7 | 5.3 ± 1.6(0.082) | 5.2 ± 1.5(0.049/> 0.05) | |
Lung | COM(mm) | 2.3 ± 1.8 | 2.3 ± 1.6(>0.05) | 2.1 ± 1.4(>0.05/> 0.05) |
DC | 0.96 ± 0.02 | 0.97 ± 0.01 (<0.001) | 0.97 ± 0.01 (<0.001/> 0.05) | |
PE | 0.07 ± 0.03 | 0.06 ± 0.03 (<0.001) | 0.06 ± 0.02 (<0.001/> 0.05) | |
HD(mm) | 16.1 ± 6.2 | 14.7 ± 5.7(0.026) | 15.2 ± 5.4(0.163/> 0.05) | |
Inter-fraction tracking (Cases 8–11) | ||||
Structures | Quantitative Metrics | RoiMod | SurphaMod ( vs RoiMod) | SurMod (vs RoiMod/SurphaMod) |
Tumor | COM(mm) | 2.1 ± 2.2 | 1.3 ± 1.3(0.028) | 1.2 ± 1.2(0.020/> 0.05) |
DC | 0.84 ± 0.12 | 0.88 ± 0.09(>0.05) | 0.89 ± 0.08(0.015/> 0.05) | |
PE | 0.37 ± 0.33 | 0.25 ± 0.21(>0.05) | 0.23 ± 0.19(0.032/> 0.05) | |
HD(mm) | 7.2 ± 2.6 | 5.7 ± 1.2(0.026) | 5.6 ± 1.1(0.013/> 0.05) | |
Lung | COM(mm) | 4.3 ± 3.0 | 3.0 ± 2.3(0.016) | 2.3 ± 1.7 (<0.001/> 0.05) |
DC | 0.95 ± 0.03 | ±0.96 ± 0.02(0.008) | 0.97 ± 0.01 (<0.001/<0.001) | |
PE | 0.11 ± 0.05 | 0.08 ± 0.04(0.004) | 0.06 ± 0.02 (<0.001/<0.001) | |
HD(mm) | 20.0 ± 8.3 | 16.7 ± 6.9(0.069) | 15.5 ± 5.9 (<0.001/> 0.05) |