Table 4 Derived parameters for arginase 1 and arginase 2 inhibition by LYS and HOMOARG

From: Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance

Enzyme

Inhibitor

IC50 ( ± SE)/mM

F-value

R2

Ki ( ± SE)/mM

F-value

R2

Arginase 1

LYS

3.64 ± 0.20

1491

0.993

1.79 ± 0.01

1358

0.992

HOMOARG

8.14 ± 0.52

584

0.983

6.10 ± 0.50

1997

0.995

Arginase 2

LYS

0.88 ± 0.01

2028

0.995

0.50 ± 0.03

1268

0.991

HOMOARG

2.52 ± 0.01

1691

0.994

1.73 ± 0.10

4114

0.997

  1. SE: standard error.
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