Figure 3
From: Inhibitory effects of superoxide dismutase 3 on Propionibacterium acnes-induced skin inflammation
SOD3 reduced the levels of pro-inflammatory cytokines in P. acnes- or PGN-treated HaCaT and SZ95 cells. HaCaT (A,B) and SZ95 (C,D) cells were pretreated with SOD3 (200 U/mL) and incubated with heat-killed P. acnes (100 MOI, black bars) or peptidoglycan (10 μg/mL, white bars) for 24 h. Expression of inflammatory cytokines was analyzed by qRT-PCR (A,C) and ELISA (B,D). All data represent the mean ± S.D. of three independent experiments *p < 0.05, **p < 0.01, ***p < 0.001.
