Table 1 Biological potency.
ADCC | ||
|---|---|---|
Protein | EC50 (μg/mL) | Relative potency (%), 95% confidence interval |
Rituximab | 0.13 | 100 |
Peak 1 | 0.20 | 80 (70.4~92.9) |
Peak 2 | 0.19 | 84 (74.0~97.6) |
Peak 3 | 0.05 | 146 (128.0~168.0) |
CDC | ||
EC 50 (μg/mL) | Relative Potency (%), 95% confidence interval | |
Rituximab | 2.3 | 100 |
Peak 1 | 5.0 | 45 (40.3~52.0) |
Peak 2 | 2.8 | 80 (70.8~91.2) |
Peak 3 | 1.9 | 117 (104.0~134.1) |
