Table 1 Association of stromal TERT expression with clinico-pathological features.

From: Association of clinicopathological features and prognosis of TERT alterations in phyllodes tumor of breast

Features N(%)

 

Low

Intermediate

High

Total

 

Age

Mean

39.0

44.5

45.1

43.0

0.022

SD

12.7

11.6

12.6

12.5

 

Median

40

45

46

44

 

Range

16–62

23–81

17–86

  

Tumor size

Mean

63.1

57.9

58.0

59.6

0.953

SD

49.3

36.5

35.5

40.5

 

Median

45.0

48

50

45

 

Range

20–250

12–220

17–180

  

Diagnosis

Benign

47(35.1)

40 (29.8)

47 (35.1)

134

0.044

Borderline

11 (22.5)

23 (46.9)

15 (30.6)

49

 

Malignant

7 (29.1)

4 (16.7)

13 (54.2)

24

 

(Borderline/malignant)

(18)

(27)

(28)

(72)

(0.270)

Total

65

67

75

207

 

Border

Pushing

39 (38.6)

29 (28.7)

33 (32.7)

101

0.086

Focal infiltrative

15 (28.8)

21(40.4)

16(30.8)

52

 

Infiltrative

5 (15.2)

12 (36.4)

16 (48.5)

33

 

Total

39

62

65

186

 

Mitotic count

<5

46 (33.5)

40 (29.2)

51 (37.2)

137

0.004

5–9

12 (27.3)

23 (52.3)

9 (20.4)

44

 

>9

7 (26.9)

4 (15.3)

15 (57.7)

26

 

Total

65

67

75

207

 

Pleomorphism

Mild

38 (39.5)

30 (31.3)

28 (29.1)

96

0.068

Moderate

24 (25.5)

33 (35.1)

37 (39.4)

94

 

Severe

3 (17.6)

4 (23.5)

10 (58.8)

17

 

Total

65

67

75

207

 

Cellularity

Mild

38 (36.2)

32 (30.5)

35 (33.3)

105

0.443

Moderate

17 (25.0)

26 (38.2)

25 (36.8)

68

 

Severe

10 (29.4)

9 (26.5)

15 (44.1)

34

 

Total

65

69

75

207

 

Stromal overgrowth

No

44 (36.7)

36 (30.0)

40 (33.3)

120

0.037

Focal

14 (26.4)

23 (43.4)

16 (30.2)

53

 

Present

7 (20.6)

8 (23.5)

19 (55.9)

34

 

Total

65

67

75

207

 

Radiotherapy

No

51 (34.5)

49 (33.1)

48 (32.4)

148

0.884

Yes

9 (30.0)

11 (36.7)

10 (33.3)

30

 

Total

60

60

58

178

 

Chemotherapy

No

60 (34.5)

58 (33.3)

56 (32.2)

174

0.367

Yes

0

2 (66.7)

1 (33.3)

3

 

Total

60

60

57

177

 
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