Table 2 Parameter estimates from the waning immunity model based on bat age in years, with 95% bootstrap confidence intervals: p0, the proportion of individuals seropositive at birth; λ, the force of infection, r i , the rate of antibody waning following natural infection; r m , the rate of antibody waning following birth.
From: Support for viral persistence in bats from age-specific serology and models of maternal immunity
R 0 | p 0 | Rates (year−1) | Mean (in years) | |||||
|---|---|---|---|---|---|---|---|---|
Waning of maternal immunity r m | Force of infection λ | Waning of acquired immunity r i | Duration of maternal immunity 1/r m | Time to acquire immunity 1/λ | Duration of acquired immunity 1/r i | |||
HeNiV | 2.1 (1.9–2.3) | 0.83 (0.73–0.93) | 1.8 (1.4–2.2) | 0.44 (0.33–0.55) | 0.24 (0.14–0.38) | 0.56 (0.45–0.70) | 2.3 (1.8–3.0) | 4.1 (2.7–7.2) |
LBV | 1.6 (1.5–1.8) | 0.41 (0.31–0.55) | 2.2 (1.4–3.3) | 0.17 (0.12–0.24) | 0.08 (0–0.19) | 0.46 (0.31–0.68) | 5.8 (4.2–7.9) | 12 (5.2 – inf.1) |
