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Figure 1

From: Central s-resistin deficiency ameliorates hypothalamic inflammation and increases whole body insulin sensitivity

Figure 1

S-resistin expression is high in the hypothalamus and increases with ageing. The expression of s-resistin (A), resistin (B) and ALBP/aP2 (C) in different tissues of 3-months old Wistar rats was determinated by qPCR using SYBRgreen or Taqman depending on the gene (see Methods section). 18S rRNA was used as endogenous control. Values are the means ± SEM; n = 4 separated determinations per group of animals, each sample made in duplicate. White adipose tissue (WAT), hypothalamus (H), liver (L), lung (Lg) and testicle (T), *p < 0,01 vs WAT (one-way ANOVA followed by Bonferroni test). Values were normalized to 1 versus WAT. (D) Hypothalamic expression of s-resistin in 24-month-aged compared to 3-month-young Wistar rats analyzed by qPCR. Values are the means ± SEM; n = 4 independent experiments per group. *p < 0,05 compare to young (Student’s t-test).

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