Table 1 Level of plasma metabolic parameters of used animals.

From: Central s-resistin deficiency ameliorates hypothalamic inflammation and increases whole body insulin sensitivity

 

EV

RNAi-s-res

NEFA (mmol/L)

1.24 ± 0.02

1.13 ± 0.03*

KB (mmol/L)

0.18 ± 0.03

0.16 ± 0.03

TAG (mg/dl)

118 ± 9

106 ± 9

Glucose (mg/dl)

106 ± 8

117 ± 5

Lactate (mmol/L)

3.8 ± 0.1

4.2 ± 0.1

Insulin (ng/ml)

1.8 ± 0.5

0.84 ± 0.1*

Resistin (ng/ml)

15 ± 1

10 ± 2*

Leptin (ng/ml)

4.8 ± 0.3

3.7 ± 0.6*

HOMA-IR

12 ± 2

6.1 ± 0.5*

IL-4 (pg/ml)

67 ± 3

86 ± 3*

IL-10 (pg/ml)

192 ± 40

222 ± 56

IL-1β (pg/ml)

36 ± 10

31 ± 8

IL-6 (pg/ml)

1469 ± 249

1375 ± 95

TNF-α (pg/ml)

3 ± 1

3 ± 1

IFN-γ (pg/ml)

1204 ± 149

857 ± 429

  1. Animals injected with the empty virus (EV) and with virus with s-resistin RNAi (RNAi-s-res). Values are the means ± SEM; n = 4–5 independent experiments per group. Biochemical determinations were made in duplicate. *p ≤ 0,05 compared to EV (Student’s t-test). NEFA: non-esterified fatty acid; KB: ketonic bodies; TAG: triacylglycerides; HOMA-IR: Homeostasis model assessment for insulin resistance.; IL: Interleukine; TNF: Tumor Necrosis Factor; IFN-γ: Interferon gamma.
Back to article page