Figure 3
K-means clustering and GO enrichment analysis of (a) atherosclerotic and (b) healthy arteries. Gene expression is presented as a colored matrix in which each row represents a gene and each column represents a sample. Green, black and red correspond to lower values, median values and higher values, respectively. Representative enriched Gene Ontology terms (FDR < 5%) are indicated within each cluster. Within each cluster, the average of all probes was calculated for each sample. These average values were then compared between the arterial territories with Student’s t-test. Inter-territorial comparisons with p < 0.01 are indicated by horizontal arrows on the left side of the clusters. White = CA = carotid artery; light gray = FA = femoral artery; dark gray = IPA = infrapopliteal artery.
