Figure 7
Two-way hierarchical clustering of control arteries and calcification-related genes. Genes were selected based on significant differential expression between the three arterial beds in control arteries (multiclass SAM analysis, FDR = 0%) and an association with bone-related functions through literature analysis or the presence of the terms ‘bone’, ‘cartilage’, ‘mineralization’ or ‘skeletal development’ in their GO categories. Gene expression is presented as a coloured matrix where each row represents a gene and each column a sample. Green, black and red correspond to lower values, median values and higher values, respectively. Colour coding of the samples is as follows: blue = carotid arteries, orange = femoral arteries, yellow = infra-popliteal arteries. The main branches of the gene and sample clusters are separated by white lines.
