Figure 9
From: Zerumbone reduces proliferation of HCT116 colon cancer cells by inhibition of TNF-alpha
(A) Physiochemical properties of zerumbone and α-humulene representing the molecular weight (MW), number of heavy atoms (NHA); fraction Csp3 (FCsp3); number of H-bond acceptors (NH-BA); molar refractivity (MR), topological polar surface area (TPSA) and XLogP3-AA. (B) Toxicity analysis of zerumbone and α-humulene on blood, cardiovascular system (CS), gastrointestinal system (GS), kidney, liver and lungs. (C) LD50 analysis of Zerumbone and α-humulene on Mouse/Intraperitoneal (M-IP); Mouse/Oral (M-O); Mouse/Intravenous (M-IV); Mouse/Subcutaneous (M-SC); Rat/Intraperitoneal (R-IP) and Rat/Oral (R-O).
