Figure 4 | Scientific Reports

Figure 4

From: Using massively parallel shotgun sequencing of maternal plasmatic cell-free DNA for cytomegalovirus DNA detection during pregnancy: a proof of concept study

Figure 4

HCMV sequencing results of the retrospective pregnant patient cohort. (A) Summary of raw sequencing results of the 538 plasma samples. The total number of sequenced reads and the total number of human sequenced reads were represented. Data are shown as Tukey boxplots. The bottom and top of the box indicates the upper and lower quartiles and the band inside the box indicates the median. (B) Mean depth on masked HCMV samples for the 538 plasma samples were represented. The grey zone represents samples with a mean depth lower than the positive threshold for detection of HCMV circulating DNA. (C) Detailed alignment of reads for positive samples. For each plot, the number of reads aligned at all HCMV genome positions (in bp) is represented.

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