Figure 1 | Scientific Reports

Figure 1

From: Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes

Figure 1

Effect of UVB on cell volume and ROS levels in REKs. (a) Images represent REKs under non-irradiated condition and 24 hours post UVB with and without organic osmolytes. (b) The cell volume of untreated and organic osmolyte- treated and UVB-exposed keratinocytes was calculated relative to non-irradiated keratinocyte volume and is presented as percentage cell volume (n = 4; mean ± SEM; *p < 0.05). (c) Increase in DCF fluorescence intensity corresponding to increase in ROS levels (n = 4; mean ± SEM; *p < 0.05). (d) Catalase (Cat), superoxide dismutase (SOD1) and glutathione peroxidase (GPx1) gene expression levels at 24 hours post UVB exposure in non-organic and organic osmolytes-treated keratinocytes (n = 3; mean ± SEM).

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