Figure 3
From: ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA
ZFP226 overexpression activates KIBRA mRNA and protein expression. KIBRA expression levels increased significantly 48 hrs after ZFP226 transfection detected by (A) real-time PCR and (B) western blot. The activating effect of ZFP226 was compared to SP1 as positive control. The cropped blots are representative for experiments (n = 4), densitometry is based on independent experiments as indicated. Beta actin was used as loading control. The respective full-length blots are shown in Supplementary Fig. S3. **p < 0.01, ***p < 0.001.
