Figure 4

MetagenomeSeq analysis. OTUs that were both identified as part of the signature by sPLS-DA/random forest and had a statistically significant Padj value (Padj < 0.05) are shown. For better visualization, CLR values were used for plotting the abundance of each OTU. The Padj values are shown in each respective panel. (a) Comparison of the control group with the HIV-infected group. (b) Comparison of the control group with the HIV-infected subgroup with high percentage of activated CD4(+) T cells.