Figure 1 | Scientific Reports

Figure 1

From: Differential expression pattern of co-inhibitory molecules on CD4+ T cells in uncomplicated versus complicated malaria

Figure 1

Higher proportions of PD-1+ and CTLA-4+ CD4+ T cells in children with complicated malaria. Blood samples from patients and controls were ex vivo analyzed for the expression of PD-1, intracellular CTLA-4, LAG-3, and Tim-3 on CD4+ T cells by flow cytometry. Box plots demonstrating expression of PD-1 (A), CTLA-4 (B), LAG-3 (C), and Tim-3 (D) in all four study groups. Statistical differences are shown according to One-way ANOVA with Tukey’s Multiple Comparison Test.

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