Figure 6
From: Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases

Inhibition of retrovirus vector yield by viral adaptor proteins. (a) The packaging cells were co-transfected with mCherry retroviral plasmids and viral adaptor protein-containing plasmids. The retrovirus vector yield was analyzed as the TCID50 as described in Materials and Methods. Data are expressed as the mean ± SE of three independent experiments. *P < 0.05 (versus time zero by Student’s t-test). (b) The expression of mCherry in retrovirus vector-infected cells was determined in hTERT-BJ1 cells. The bar indicates 50 µm.