Figure 7
From: Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases
CD3ε down-regulation by herpesvirus-encoding membrane proteins. JM cells were transfected with a bicistronic transcript plasmid encoding herpesvirus proteins (a) HSV-1 UL56; (b) VZV ORF0; (c) HCMV UL42; (d) HHV-6A U24 and the PA mutants) and ZsGreen1 (Vector). Twenty-four hours post-transfection, surface CD3ε (OKT7) expression in cells displaying ZsGreen1 expression was analyzed by flow cytometry.
