Table 5 Clinical lab phenotypic variables tested for PheWAS.
From: Rare variants in drug target genes contributing to complex diseases, phenome-wide
| Â | Clinical Lab Trait | Transformation |
|---|---|---|
1 | Alanine aminotransferase - serum plasma | Natural Log |
2 | Albumin - serum plasma | Natural Log |
3 | Alkaline phosphatase - serum plasma | Natural Log |
4 | Anion GAP - serum plasma | — |
5 | Aspartate aminotransferase (AST) - serum plasma | Natural Log |
6 | Bilirubin - serum plasma 0.001 | Natural Log |
7 | Calcium (Ca) - serum plasma | — |
8 | CARBON_DIOXIDE_CO2_SERUM_PLASMA | — |
9 | Chloride (Cl) - serum plasma | — |
10 | Creatinine (eGFR) - serum plasma | Natural Log |
11 | Erythrocyte Distribution Width (RDW) - blood | Natural Log |
12 | Hematocrit (HCT) - blood | — |
13 | Hemoglobin - blood | — |
14 | Mean corpuscular hemoglobin concentration (MCHC) - blood | — |
15 | Mean corpuscular hemoglobin (MCH) - blood | — |
16 | Mean corpuscular volume (MCV) - blood | — |
17 | Platelet blood count | — |
18 | Platelet mean volume (MPV) - blood | — |
19 | Potassium (K) - serum plasma | — |
20 | Protein - serum plasma | — |
21 | Red Blood Cell (RBC) count - blood | — |
22 | Sodium (Na) - serum plasma | — |
23 | Urea Nitrogen - serum plasma | — |
24 | White Blood Cell (WBC) count - blood 0.001 | Log |
25 | Fasting Blood Glucose (FBG) | Boxcox |
26 | Hemoglobin A1C (HBA1C) | Boxcox |
27 | Cholesterol | Natural Log |
28 | Free T3 | Natural Log |
29 | Free T4 | Natural Log |
30 | Bicarbonate (HCO3) | Natural Log |
31 | High Density Lipoprotein (HDL) | Natural Log |
32 | Insulin-like growth factor (IGF1) | Natural Log |
33 | Low density lipoprotein (LDL) | Natural Log |
34 | Triglycerides (TRIG) | Natural Log |
35 | Thyroid stimulating hormone (TSH) | Natural Log |
