Figure 3

Heat map of the metabolites from the evolved strain W303-1b/FGPPT-8–12 obtained from the ALE experiments and the parental strain W303-1b/FGPPT. Rows represent specific intracellular metabolites. Columns represent different cell growth intervals (12, 24, 36, 48 and 60 h). Fold change was used to evaluate the relative concentration of metabolites of W303-1b/FGPPT-8–12 and W303-1b/FGPPT.