Figure 8
From: Loss of ezrin expression reduced the susceptibility to the glomerular injury in mice
Morphological analysis of FL-ezrin and T567D-ezrin transfected E11 cells. E11 cells transfected with FL-ezrin (a) and T567D-ezrin (b) were double-stained with an anti-flag antibody (green) and rhodamine-phalloidin (red). Both FL-ezrin and T567D-ezrin were detected at the cellular cortex. Some protrusions were observed in FL-ezrin-transfected E11 cells (a), while enhanced membrane ruffling was observed in T567D-ezrin transfected E11 cells (white arrow) (b). The number of lamellipodia per cell was counted. Lamellipodia were defined as 3- to 10-μm regions located at the cell periphery, as previously described by Raucher et al.
