Figure 2
From: De Novo Design of Potent, Insecticidal Synthetic Mimics of the Spinosyn Macrolide Natural Products

3D-structures and overlay of 21-butyl spinosyn A (6), the initial PBI-based spinosyn scaffold (4) and the synthetic spinosyn mimic (5) possessing a triaryl replacement for the spinosyn macrocycle. All of the structures 4, 5, 6 are aligned to the 2′, 3′, 4′-tri-O-methyl rhamnose.