Figure 5

(A) Effect of Nrf2 activator, resveratrol on nuclear translocation of Nrf2 in cytokine cocktail-treated pancreatic β-cells. (B) Glucose-stimulated insulin secretion assay were performed in Krebs-Ringer bicarbonate buffer containing low (2.8 mM) and high (28 mM) glucose concentrations to study the effect of Nrf2 activator on insulin secretion in cytokine exposed cells. Data are expressed as mean ± SEM of three separate experiments. Statistical analysis was performed using one way ANOVA. p < 0.05.