Figure 2

HIV-1CZA Integrase mutation profiling. Integrase mutation profiling of consensus sequences generated using the database-derived HIV-1CZA sequences HIV-1B (n = 5278), HIV-1C (n = 1416), cohort sequences HIV-1C-ZA (n = 87) identified 17 naturally occurring polymorphisms D25E, V31I, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A and S283G. Among the 17 mutations 11 were further increased in our cohort