Table 2 X-linked genes with immune function and non-significant sex-based DNA methylation in the nasal airway of infants and children.
From: Characterization of Sex-Based Dna Methylation Signatures in the Airways During Early Life
Gene | Gene name | Xi status | Aec | Primary site |
|---|---|---|---|---|
DDX3X | DEAD-box helicase 3, X-linked | Escape | Yes | Ubiquitous |
PRKX | cAMP-dependent protein kinase catalytic subunit | Escape | Yes | Ubiquitous |
TXLNG | Gamma-taxilin | Escape | Yes | Ubiquitous |
L1CAM | Neural cell adhesion molecule L1 | Escape | Yes | Neurons, immune cells |
VEGFD | Vascular endothelial growth factor D | Heterogeneous | Yes | Ubiquitous |
TIMP1 | Metalloproteinase inhibitor 1 | Heterogeneous | Yes | Ubiquitous |
TLR7 | Toll-like receptor 7 | Heterogeneous | Yes | Ubiquitous |
BTK | Tyrosine-protein kinase BTK | Heterogeneous | N/A | Lymphocytes |
BMP15 | Bone morphogenetic protein 15 | Heterogeneous | N/A | Testis |
DDX53 | DEAD-box helicase 53, X-linked | Heterogeneous | N/A | Testis |
AKAP4 | A-kinase anchor protein 4 | Heterogeneous | N/A | Cancer/Testis |
SRPX2 | Sushi repeat-containing protein | Heterogeneous | N/A | Ubiquitous |
GRPR | Gastrin-releasing peptide receptor | Heterogeneous | N/A | Ubiquitous |
CD40LG | CD40 ligand | Heterogeneous | N/A | Ubiquitous |
CTAG2 | Cancer/testis antigen 2 | Heterogeneous | N/A | Cancer/Testis |
CXorf36 | Deleted in autism-related protein 1 | Heterogeneous | N/A | Neurons, ovary |
