Figure 4 | Scientific Reports

Figure 4

From: Cancer Vaccine Therapy Using Carcinoembryonic Antigen - expressing Dendritic Cells generated from Induced Pluripotent Stem Cells

Figure 4

Cytotoxic activity of cytotoxic T cells generated from hiPSDCs-CEA against gastrointestinal cancer cell lines endogenously expressing CEA. The cytotoxic T cells induced by hiPSDCs-CEA from each of the three HLA-A24-positive donors exhibited cytotoxic activity against MKN45 and HT29, which endogenously expressed CEA and possessed the HLA-A24 allele, whereas they showed no cytotoxicity against MKN1, which did not endogenously express CEA and possessed the HLA-A24 allele.

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