Figure 2 | Scientific Reports

Figure 2

From: Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion

Figure 2

Expression of renal injury and pro-inflammatory markers. (A) Renal mRNA levels of lipocalin 2 (Lcn2; also known as neutrophil gelatinase–associated lipocalin [Ngal]), (B) kidney injury molecule 1 (Kim1) and pro–inflammatory cytokine (C) interleukin 1 beta (Il1b) and (D) Il6 and (E) tumor necrosis factor (Tnf) in sham and in Trpv4 KO and WT mice following IRI. Renal gene expression data are determined in n = 4 for sham-operated WT and Trpv4 KO mice and n = 6 for I/R–injured WT and Trpv4 KO mice, two-way ANOVA. In all cases PTreatment < 0.001, and PGenotype and PInteraction are not significant.

Back to article page