Table 1 Affinities to FcRn and MSA.
From: In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor
Construct | Target | KD (nM) | KD (nM) |
|---|---|---|---|
pH 6.0 | pH 7.4 | ||
ZFcRn | hFcRn | 8.7 | 365 |
MSA | N.B.a | N.B. | |
ZFcRn-ABD | hFcRn | 3.3 | 36 |
MSA | 0.3 | 0.5 |
From: In vivo depletion of serum IgG by an affibody molecule binding the neonatal Fc receptor
Construct | Target | KD (nM) | KD (nM) |
|---|---|---|---|
pH 6.0 | pH 7.4 | ||
ZFcRn | hFcRn | 8.7 | 365 |
MSA | N.B.a | N.B. | |
ZFcRn-ABD | hFcRn | 3.3 | 36 |
MSA | 0.3 | 0.5 |
