Table 2 Properties and Baseline Clinical Characteristics of Iranian Patients based on HHpgV-1 positivity.
From: First detection of human hepegivirus-1 (HHpgV-1) in Iranian patients with hemophilia
Variables | IHP-16 | IHP-234 | IHP-343 | IHP-381 | Total population (mean ± SD) | P-value |
|---|---|---|---|---|---|---|
Sex | Male | Male | Male | Male | — | 0.305 |
Age (years) | 62.0 | 68.0 | 71.0 | 64.0 | 66.3 ± 4.0 | 0.001* |
ALT (IU/L) | 59.0 | 48.0 | 47.0 | 61.0 | 53.8 ± 7.3 | 0.542 |
AST (IU/L) | 55.0 | 50.0 | 42.0 | 48.0 | 48.8 ± 5.4 | 0.547 |
ALK (IU/L) | 350.0 | 342.0 | 384.0 | 280.0 | 339.0 ± 43.3 | 0.118 |
HCV genotype | HCV-1a | HCV-1a | HCV-1a | HCV-1a | — | 0.002* |
HCV viral load (IU/mL) | 4.0 × 105 | 3.5 × 105 | 5.3 × 105 | 4.3 × 105 | 4.3 × 105 ± 0.7 × 105 | 0.010* |
HPgV-1 viral load (log RNA copies/mL) | 5.9 | 5.9 | 6.0 | 5.4 | 5.2 ± 1.3 | <0.001* |
TTV positivity | Yes | Yes | Yes | Yes | — | 0.001* |
HHpgV-1 viral load (log RNA copies/mL) | 4.9 | 4.8 | 4.6 | 5.4 | 4.9 ± 0.3 | <0.001* |
Severity of fibrosis | F0 | F0 | F1 | F0 | — | 0.001* |
